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Starting a supplement brand is exciting yet costly.

Many entrepreneurs wonder about its exact startup cost.

The truth is, there is no fixed number.

It varies based on multiple key factors.

These factors include product type, manufacturing method, and compliance.

This article breaks down all related costs clearly.

It also provides practical data and tips for beginners.

1. Core Factors Affecting Startup Costs

Before calculating costs, you need to understand key influences.

Each choice you make will change the total budget.

Product Type: Basic supplements cost less than specialized ones. 例えば, a vitamin C tablet is cheaper than a custom probiotic blend.
Manufacturing Model: OEM/ODM is more cost-effective for beginners than building your own factory.
Compliance Requirements: Different regions have different regulations, which affect testing and registration fees.
Brand Scale: A small online brand needs less budget than a full-scale national brand.
Distribution Channels: Online sales cost less than offline retail (例えば, 薬局, supermarkets).

2. Detailed Breakdown of Startup Costs

Below is a detailed cost breakdown by category.

All data is based on 2025-2026 industry research.

2.1 Brand Registration & Legal Fees

This is the first step and cannot be skipped.

It includes company registration, trademark, and legal consultation.

Cost Item	Cost Range (USD)	Notes & Data Source
Company Registration	200 – 1,500	Depends on region; includes license and stamp fees (ソース 1, 5)
Trademark Registration	225 – 600	Official fee plus optional agent fee (ソース 1)
Legal Consultation	500 – 3,000	For compliance and contract review (ソース 5)
Total	925 – 5,100	Average: ~$3,000

2.2 Product Development & Compliance Costs

Compliance is critical in the supplement industry.

Testing and registration ensure product safety and legality.

2.2.1 Formula & Development Fees

If you use existing formulas, this cost can be avoided.

Custom formulas require R&D investment.

Existing formula (OEM): $0 – $500 (agent service fee)
Custom formula (R&D): $1,000 – $10,000 (depends on complexity, ソース 3)

2.2.2 Testing & Certification Fees

Every supplement must pass safety and quality tests.

Fees vary by test type and product category.

Test Type	Cost Range (USD)	Data Source
Microbial & Heavy Metal Testing	300 – 800 per product	ソース 3, 4, 7
Efficacy Ingredient Testing	500 – 1,500 per product	ソース 3, 4
Stability Testing	1,000 – 3,000 per product	ソース 3, 4
GMP Certification (if needed)	5,000 – 20,000	ソース 5, 7

2.2.3 Registration &De-registration Fees

Different regions have different registration requirements.

Below are common regions’ fee ranges.

US (FDA Registration): $2,000 – $5,000 per product (ソース 4, 6)
EU (CE Marking): $1,500 – $4,000 per product (ソース 4)
China (Health Food Registration): $15,000 – $45,000 per product (ソース 4)
Australia (TGA Registration): $3,000 – $8,000 per product (ソース 3)

2.3 Manufacturing Costs

Manufacturing is the largest cost for most brands.

It depends on production volume, dosage form, and raw materials.

2.3.1 Raw Material Costs

Raw materials account for 5%-60% of manufacturing costs.

High-quality or imported raw materials are more expensive.

Raw Material Type	Cost Range (USD/kg)	Data Source
Basic Vitamins (例えば, Vitamin C)	5 – 20	ソース 2, 3
Minerals (例えば, Calcium, Iron)	8 – 30	ソース 2, 3
植物エキス (例えば, Green Tea Extract)	50 – 200	ソース 2, 3
Probiotics (例えば, Lactobacillus)	200 – 800	ソース 2, 3

2.3.2 Production & Processing Fees

Processing fees vary by dosage form and order quantity.

Larger orders usually get lower unit prices.

タブレット: $0.05 – $0.08 per unit (ソース 7)
Hard Capsules: $0.07 – $0.12 per unit (ソース 3, 7)
Soft Capsules: $0.10 – $0.18 per unit (ソース 3, 7)
粉末: $0.20 – $0.50 per package (ソース 7)
Minimum Order Quantity (MOQ): 5,000 – 50,000 units (ソース 3)

2.4 包装 & Labeling Costs

Packaging affects both cost and brand image.

You can choose basic or custom packaging based on budget.

Packaging Item	Cost Range (USD)	Notes
PET Bottles (100-count)	0.50 – 1.50 per bottle	Basic type; custom design adds 20%-50%
Glass Bottles (100-count)	1.20 – 3.00 per bottle	More expensive but premium-looking
Labels & Manuals	0.05 – 0.20 per unit	Must comply with regional labeling rules (ソース 3, 5)
Outer Cartons	1.00 – 3.00 per carton	For transportation and storage

2.5 Marketing & Sales Costs

Even great products need marketing to reach customers.

Marketing costs account for 40%-60% of total budget (ソース 2).

2.5.1 Online Marketing

Online channels are cost-effective for new brands.

ソーシャルメディア (インスタグラム, TikTok, フェイスブック): $500 – $5,000/month (ads + content)
E-commerce Platforms (アマゾン, ショッピファイ): $300 – $2,000/month (fees + ads, ソース 5, 6)
Influencer Collaboration: $100 – $10,000 per influencer (depends on followers, ソース 6)
Content Creation (Videos, Blogs): $200 – $2,000/month

2.5.2 Offline Marketing (Optional)

Offline marketing is more expensive but builds trust.

Pharmacy & Supermarket Entry Fees: $1,000 – $10,000 per channel (ソース 5)
Trade Shows & Exhibitions: $2,000 – $15,000 per event
Printed Materials (Flyers, Brochures): $500 – $2,000

2.6 Operational Costs (First 6 Months)

You need to prepare for daily operations.

These costs keep your brand running smoothly.

Warehousing: $200 – $1,500/month (depends on volume, ソース 5)
Logistics & Shipping: $300 – $3,000/month (ソース 2, 5)
Staff Salaries (part-time/full-time): $1,000 – $8,000/month (ソース 5)
Software & ツール (Inventory, Accounting): $50 – $300/month (ソース 5)
Emergency Reserve: 10%-20% of total budget (ソース 3, 5)

3. Total Startup Cost Estimates by Brand Scale

Based on the above breakdown, here are total cost ranges.

They help you choose the right scale for your budget.

Brand Scale	Cost Range (USD)	Key Features
Micro Brand (Online Only, 1-2 製品)	10,000 – 30,000	OEM manufacturing, basic packaging, social media marketing (ソース 3, 5)
Small Brand (Online + Local Offline, 3-5 製品)	30,000 – 80,000	Custom formulas, moderate marketing, local pharmacy entry (ソース 2, 5)
Medium Brand (National Online + Offline, 5-10 製品)	80,000 – 200,000	GMP certification, multi-channel marketing, large production volume (ソース 3, 6)
Large Brand (International, 10+ 製品)	200,000+	Global registration, celebrity endorsements, own R&D team (ソース 3, 6)

4. Money-Saving Tips for Beginners

Starting a supplement brand does not need to be overpriced.

Here are practical tips to cut unnecessary costs.

Choose OEM/ODM instead of building your own factory. It saves 50%-70% of manufacturing costs (ソース 3).
Start with 1-2 core products. Avoid expanding too fast to reduce R&D and inventory costs.
Use basic packaging first. Upgrade to custom designs after gaining sales (ソース 3).
Focus on social media marketing. It is cheaper than TV ads or celebrity endorsements (ソース 6).
Cooperate with small-scale manufacturers. They often offer lower MOQs and better discounts (ソース 3).
Plan your production in advance. Avoid urgent orders that increase costs (ソース 3).

5. Risks to Consider

Cost overruns are common for new supplement brands.

You need to anticipate these risks to avoid budget issues.

Raw material price fluctuations: Some ingredients may rise by 20%-30% (ソース 3, 6).
Compliance changes: New regulations may require additional testing (ソース 4, 6).
Inventory waste: Unsold products may expire, leading to losses (ソース 5).
Marketing inefficiency: High ad costs with low sales (ソース 6).